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(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule with the chemical formula C23H21N5O and a molecular weight of approximately 383.4 g/mol. It is listed in DrugBank as an experimental drug under the accession number DB06977, but there are no approved indications or marketed uses reported. The structure features an indazole, pyridine, and indole moiety connected via an ether linkage to a chiral propanamine backbone. According to DrugBank, it has been studied for its interaction with cAMP-dependent protein kinase catalytic subunit alpha in humans; however, its precise mechanism of action and pharmacological effects remain uncharacterized in public databases as of June 2025[1][2][10]. No clinical development or therapeutic application has been established.

Other names
(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)(2S)-1-{[5-(1H-Indazol-5-Yl)pyridin–3-Yl]oxy}-3–[(7as)–7ah-Indol–3-Yl]propan–2-Amine(2S)-1-[7aH-indol–3–yl]- { [ 5 –( 2 H –indazol –5 – yl )pyridin – 3 – yl ] oxy } propan - 2 - amine
02

Targets

PKA (Cyclic amp-dependent protein kinase)

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